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Accelerated Recovery of Mitochondrial Membrane Potential by GSK-3β Inactivation Affords Cardiomyocytes Protection from Oxidant-Induced Necrosis

Loss of mitochondrial membrane potential (ΔΨ(m)) is known to be closely linked to cell death by various insults. However, whether acceleration of the ΔΨ(m) recovery process prevents cell necrosis remains unclear. Here we examined the hypothesis that facilitated recovery of ΔΨ(m) contributes to cytop...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Sunaga, Daisuke, Tanno, Masaya, Kuno, Atsushi, Ishikawa, Satoko, Ogasawara, Makoto, Yano, Toshiyuki, Miki, Takayuki, Miura, Tetsuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229200/
https://ncbi.nlm.nih.gov/pubmed/25390651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112529
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