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CCR2 Elimination in Mice Results in Larger and Stronger Tibial Bones but Bone Loss is not Attenuated following Ovariectomy or Muscle Denervation

Bone loss due to age and disuse contributes to osteoporosis and increases fracture risk. It has been hypothesized that such bone loss can be attenuated by modulation of the C-C chemokine receptor 2 (CCR2) and/or its ligands. The objectives of this study were to examine the effects of genetic elimina...

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Библиографические подробности
Опубликовано в: :Calcif Tissue Int
Главные авторы: Mader, Tara L., Novotny, Susan A., Lin, Angela S., Guldberg, Robert E., Lowe, Dawn A., Warren, Gordon L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228687/
https://ncbi.nlm.nih.gov/pubmed/25234653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-014-9914-z
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