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CCR2 Elimination in Mice Results in Larger and Stronger Tibial Bones but Bone Loss is not Attenuated following Ovariectomy or Muscle Denervation

Bone loss due to age and disuse contributes to osteoporosis and increases fracture risk. It has been hypothesized that such bone loss can be attenuated by modulation of the C-C chemokine receptor 2 (CCR2) and/or its ligands. The objectives of this study were to examine the effects of genetic elimina...

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Detalhes bibliográficos
Publicado no:Calcif Tissue Int
Main Authors: Mader, Tara L., Novotny, Susan A., Lin, Angela S., Guldberg, Robert E., Lowe, Dawn A., Warren, Gordon L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228687/
https://ncbi.nlm.nih.gov/pubmed/25234653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-014-9914-z
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