Ca(2+)-inhibitable adenylyl cyclase modulates pulmonary artery endothelial cell cAMP content and barrier function.

Maintenance by the endothelium of a semi-permeable barrier is critically important in the exchange of oxygen and carbon dioxide in the lung. Intracellular free Ca2+ ([Ca2+]i) and cAMP are principal determinants of endothelial cell barrier function through their mutually opposing actions on endotheli...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Stevens, T, Nakahashi, Y, Cornfield, D N, McMurtry, I F, Cooper, D M, Rodman, D M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42285/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708708/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2696
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