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Identification of direction in gene networks from expression and methylation

BACKGROUND: Reverse-engineering gene regulatory networks from expression data is difficult, especially without temporal measurements or interventional experiments. In particular, the causal direction of an edge is generally not statistically identifiable, i.e., cannot be inferred as a statistical pa...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Simcha, David M, Younes, Laurent, Aryee, Martin J, Geman, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228359/
https://ncbi.nlm.nih.gov/pubmed/24182195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-118
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