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Identification of direction in gene networks from expression and methylation

BACKGROUND: Reverse-engineering gene regulatory networks from expression data is difficult, especially without temporal measurements or interventional experiments. In particular, the causal direction of an edge is generally not statistically identifiable, i.e., cannot be inferred as a statistical pa...

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Bibliografiske detaljer
Udgivet i:BMC Syst Biol
Main Authors: Simcha, David M, Younes, Laurent, Aryee, Martin J, Geman, Donald
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228359/
https://ncbi.nlm.nih.gov/pubmed/24182195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-118
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