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Merging concepts - coupling an agent-based model of hematopoietic stem cells with an ODE model of granulopoiesis

BACKGROUND: Hematopoiesis is a complex process involving different cell types and feedback mechanisms mediated by cytokines. This complexity stimulated various models with different scopes and applications. A combination of complementary models promises to provide their mutual confirmation and to ex...

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Pubblicato in:BMC Syst Biol
Autori principali: Krinner, Axel, Roeder, Ingo, Loeffler, Markus, Scholz, Markus
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228322/
https://ncbi.nlm.nih.gov/pubmed/24180697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-117
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