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Free-energy landscape of the GB1 hairpin in all-atom explicit solvent simulations with different force fields: Similarities and differences

Although it is now possible to fold peptides and miniproteins in molecular dynamics simulations, it is well appreciated that force fields are not all transferable to different proteins. Here, we investigate the influence of the protein force field and the solvent model on the folding energy landscap...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Best, Robert B., Mittal, Jeetain
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228318/
https://ncbi.nlm.nih.gov/pubmed/21322056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22972
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