Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is characterised by hypoxia, which activates gene transcription through hypoxia-inducible factors (HIF), as well as by expression of epidermal growth factor (EGF) and EGF receptors, targeting of which has been demonstrated to provide therapeutic benefit in CRC. Al...

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發表在:BMC Cancer
Main Authors: Khong, Tak L, Thairu, Ngayu, Larsen, Helene, Dawson, Peter M, Kiriakidis, Serafim, Paleolog, Ewa M
格式: Artigo
語言:Inglês
出版: BioMed Central 2013
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228238/
https://ncbi.nlm.nih.gov/pubmed/24180698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-518
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