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Titrating T cell Epitopes within Self-Assembled Vaccines Optimizes CD4+ Helper T Cell and Antibody Outputs
Epitope content plays a critical role in determining T cell and antibody responses to vaccines, biomaterials, and protein therapeutics, but its effects are nonlinear and difficult to isolate. Here, molecular self-assembly was used to build a vaccine with precise control over epitope content, in orde...
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| Publicado no: | Adv Healthc Mater |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4227912/ https://ncbi.nlm.nih.gov/pubmed/24923735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201400137 |
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