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Targeting pathways downstream of KRAS in lung adenocarcinoma

Oncogenic KRAS activation is responsible for the most common genetic subtype of lung cancer. Although many of the major downstream signaling pathways that KRAS engages have been defined, these discoveries have yet to translate into effective targeted therapy. Much of the current focus has been direc...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics
Principais autores: Zhu, Zehua, Golay, Hadrien G, Barbie, David A
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227881/
https://ncbi.nlm.nih.gov/pubmed/25303301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.14.108
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