Analysis of Nidogen-1/Laminin γ1 Interaction by Cross-Linking, Mass Spectrometry, and Computational Modeling Reveals Multiple Binding Modes

We describe the detailed structural investigation of nidogen-1/laminin γ1 complexes using full-length nidogen-1 and a number of laminin γ1 variants. The interactions of nidogen-1 with laminin variants γ1 LEb2–4, γ1 LEb2–4 N836D, γ1 short arm, and γ1 short arm N836D were investigated by applying a co...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lössl, Philip, Kölbel, Knut, Tänzler, Dirk, Nannemann, David, Ihling, Christian H., Keller, Manuel V., Schneider, Marian, Zaucke, Frank, Meiler, Jens, Sinz, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227867/
https://ncbi.nlm.nih.gov/pubmed/25387007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112886
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