Adherence to the first-AUG rule when a second AUG codon follows closely upon the first.
The rule that eukaryotic ribosomes initiate translation exclusively at the 5' proximal AUG codon is abrogated under rare conditions. One circumstance that has been suggested to allow dual initiation is close apposition of a second AUG codon. A possible mechanism might be that the scanning 40S riboso...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42278/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708701/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2662 |
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