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Chemical probing of RNA with the hydroxyl radical at single-atom resolution

While hydroxyl radical cleavage is widely used to map RNA tertiary structure, lack of mechanistic understanding of strand break formation limits the degree of structural insight that can be obtained from this experiment. Here, we determine how individual ribose hydrogens of sarcin/ricin loop RNA par...

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Foilsithe in:Nucleic Acids Res
Main Authors: Ingle, Shakti, Azad, Robert N., Jain, Swapan S., Tullius, Thomas D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2014
Ábhair:
RNA
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227780/
https://ncbi.nlm.nih.gov/pubmed/25313156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku934
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