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Chemical probing of RNA with the hydroxyl radical at single-atom resolution

While hydroxyl radical cleavage is widely used to map RNA tertiary structure, lack of mechanistic understanding of strand break formation limits the degree of structural insight that can be obtained from this experiment. Here, we determine how individual ribose hydrogens of sarcin/ricin loop RNA par...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ingle, Shakti, Azad, Robert N., Jain, Swapan S., Tullius, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227780/
https://ncbi.nlm.nih.gov/pubmed/25313156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku934
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