Oligodendrocyte Precursor Cells Modulate the Neuronal Network by Activity-Dependent Ectodomain Cleavage of Glial NG2

The role of glia in modulating neuronal network activity is an important question. Oligodendrocyte precursor cells (OPC) characteristically express the transmembrane proteoglycan nerve-glia antigen 2 (NG2) and are unique glial cells receiving synaptic input from neurons. The development of NG2+ OPC...

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Udgivet i:PLoS Biol
Main Authors: Sakry, Dominik, Neitz, Angela, Singh, Jeet, Frischknecht, Renato, Marongiu, Daniele, Binamé, Fabien, Perera, Sumudhu S., Endres, Kristina, Lutz, Beat, Radyushkin, Konstantin, Trotter, Jacqueline, Mittmann, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227637/
https://ncbi.nlm.nih.gov/pubmed/25387269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001993
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