CD44 promotes Kras-dependent lung adenocarcinoma

Kras-induced non-small-cell lung adenocarcinoma is the major subtype of lung cancers and is associated with poor prognosis. Using a lung cancer mouse model that expresses a cre-mediated Kras(G12D) mutant, we identified a critical role for the cell surface molecule CD44 in mediating cell proliferatio...

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Bibliografiska uppgifter
I publikationen:Oncogene
Huvudupphovsmän: Zhao, P, Damerow, MS, Stern, P, Liu, AH, Sweet-Cordero, A, Siziopikou, K, Neilson, JR, Sharp, PA, Cheng, C
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227610/
https://ncbi.nlm.nih.gov/pubmed/23208496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.542
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