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Towards Global QSAR Model Building for Acute Toxicity: Munro Database Case Study

A series of 436 Munro database chemicals were studied with respect to their corresponding experimental LD(50) values to investigate the possibility of establishing a global QSAR model for acute toxicity. Dragon molecular descriptors were used for the QSAR model development and genetic algorithms wer...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chavan, Swapnil, Nicholls, Ian A., Karlsson, Björn C. G., Rosengren, Annika M., Ballabio, Davide, Consonni, Viviana, Todeschini, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227209/
https://ncbi.nlm.nih.gov/pubmed/25302621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms151018162
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