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Acute Toxicity-Supported Chronic Toxicity Prediction: A k-Nearest Neighbor Coupled Read-Across Strategy

A k-nearest neighbor (k-NN) classification model was constructed for 118 RDT NEDO (Repeated Dose Toxicity New Energy and industrial technology Development Organization; currently known as the Hazard Evaluation Support System (HESS)) database chemicals, employing two acute toxicity (LD(50))-based cla...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Chavan, Swapnil, Friedman, Ran, Nicholls, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463722/
https://ncbi.nlm.nih.gov/pubmed/26006240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160511659
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