Tanshinone IIA Pretreatment Renders Free Flaps against Hypoxic Injury through Activating Wnt Signaling and Upregulating Stem Cell-Related Biomarkers

Partial or total flap necrosis after flap transplantation is sometimes clinically encountered in reconstructive surgery, often as a result of a period of hypoxia that exceeds the tolerance of the flap tissue. In this study, we determine whether tanshinone IIA (TSA) pretreatment can protect flap tiss...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Xu, Zihan, Zhang, Zhenxin, Wu, Lijun, Sun, Yaowen, Guo, Yadong, Qin, Gaoping, Mu, Shengzhi, Fan, Ronghui, Wang, Benfeng, Gao, Wenjie
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227206/
https://ncbi.nlm.nih.gov/pubmed/25302618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms151018117
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