Tanshinone IIA pretreatment protects free flaps against hypoxic injury by upregulating stem cell-related biomarkers in epithelial skin cells

BACKGROUND: Partial or total flap necrosis after flap transplantation is sometimes encountered in reconstructive surgery, often as a result of a period of hypoxia that exceeds the tolerance of the flap tissue. The purpose of this study was to determine whether Tanshinone IIA (TSA) pretreatment can p...

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Bibliographic Details
Main Authors: Xu, Zihan, Wu, Lijun, Sun, Yaowen, Guo, Yadong, Qin, Gaoping, Mu, Shengzhi, Fan, Ronghui, Wang, Benfeng, Gao, Wenjie, Zhang, Zhenxin
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162953/
https://ncbi.nlm.nih.gov/pubmed/25186638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-14-331
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