Prognostic impact of MGMT promoter methylation and MGMT and CD133 expression in colorectal adenocarcinoma

BACKGROUND: New biomarkers are needed for the prognosis of advanced colorectal cancer, which remains incurable by conventional treatments. O(6)-methylguanine DNA methyltransferase (MGMT) methylation and protein expression have been related to colorectal cancer treatment failure and tumor progression...

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Vydáno v:BMC Cancer
Hlavní autoři: Oliver, Jaime Antonio, Ortiz, Raúl, Melguizo, Consolación, Álvarez, Pablo Juan, Gómez-Millán, Jaime, Prados, Jose
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227111/
https://ncbi.nlm.nih.gov/pubmed/25015560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-511
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