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Improvement of L-phenylalanine production from glycerol by recombinant Escherichia coli strains: The role of extra copies of glpK, glpX, and tktA genes

BACKGROUND: For the production of L-phenylalanine (L-Phe), two molecules of phosphoenolpyruvate (PEP) and one molecule erythrose-4-phosphate (E4P) are necessary. PEP stems from glycolysis whereas E4P is formed in the pentose phosphate pathway (PPP). Glucose, commonly used for L-Phe production with r...

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Detalles Bibliográficos
Publicado en:Microb Cell Fact
Main Authors: Gottlieb, Katrin, Albermann, Christoph, Sprenger, Georg A
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227036/
https://ncbi.nlm.nih.gov/pubmed/25012491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-014-0096-1
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