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Improved Production of Tryptophan in Genetically Engineered Escherichia coli with TktA and PpsA Overexpression

Intracellular precursor supply is a critical factor for amino acid productivity. In the present study, ppsA and tktA genes were overexpressed in genetically engineered Escherichia coli to enhance the availability of two precursor substrates, phosphoenolpyruvate and erythrose-4-phosphate. The enginee...

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Detalhes bibliográficos
Main Authors: Shen, Tong, Liu, Qing, Xie, Xixian, Xu, Qingyang, Chen, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390157/
https://ncbi.nlm.nih.gov/pubmed/22791961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/605219
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