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Receptor-interacting protein kinase 3 deficiency inhibits immune cell infiltration and attenuates organ injury in sepsis

INTRODUCTION: Sepsis is defined as a systemic hyper-inflammatory immune response, with a subsequent immune-suppressive phase, which leads to multiple organ dysfunction and late lethality. Receptor-interacting protein kinase 3 (RIPK3)-dependent necrosis is implicated in driving tumor necrosis factor...

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Bibliographische Detailangaben
Veröffentlicht in:Crit Care
Hauptverfasser: Sharma, Archna, Matsuo, Shingo, Yang, Weng-Lang, Wang, Zhimin, Wang, Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226938/
https://ncbi.nlm.nih.gov/pubmed/24996547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc13970
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