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The DEAD box helicase RDE-12 promotes amplification of RNAi in cytoplasmic foci in C. elegans

RNA interference (RNAi) is a potent mechanism for down-regulating gene expression. Conserved RNAi pathway components are found in animals, plants, fungi and other eukaryotes [1–3]. In C. elegans, the RNAi response is greatly amplified by the synthesis of abundant secondary siRNAs [4–6]. Exogenous do...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Yang, Huan, Vallandingham, Jim, Shiu, Philip, Li, Hua, Hunter, Craig P., Mak, Ho Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226741/
https://ncbi.nlm.nih.gov/pubmed/24684930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.01.008
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