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The DEAD box helicase RDE-12 promotes amplification of RNAi in cytoplasmic foci in C. elegans
RNA interference (RNAi) is a potent mechanism for down-regulating gene expression. Conserved RNAi pathway components are found in animals, plants, fungi and other eukaryotes [1–3]. In C. elegans, the RNAi response is greatly amplified by the synthesis of abundant secondary siRNAs [4–6]. Exogenous do...
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| Publicado en: | Curr Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4226741/ https://ncbi.nlm.nih.gov/pubmed/24684930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.01.008 |
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