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Selective JAK2/ABL dual inhibition therapy effectively eliminates TKI-insensitive CML stem/progenitor cells
Imatinib Mesylate (IM) and other tyrosine kinase inhibitor (TKI) therapies have had a major impact on the treatment of chronic myeloid leukemia (CML). However, TKI monotherapy is not curative, with relapse and persistence of leukemic stem cells (LSCs) remaining a challenge. We have recently identifi...
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Gepubliceerd in: | Oncotarget |
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Hoofdauteurs: | , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Impact Journals LLC
2014
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4226710/ https://ncbi.nlm.nih.gov/pubmed/25226617 |
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