A screen for transcription factor targets of Glycogen Synthase Kinase-3 highlights an inverse correlation of NFκB and Androgen Receptor Signaling in Prostate Cancer

Expression of Glycogen Synthase Kinase-3 (GSK-3) is elevated in prostate cancer and its inhibition reduces prostate cancer cell proliferation, in part by reducing androgen receptor (AR) signaling. However, GSK-3 inhibition can also activate signals that promote cell proliferation and survival, which...

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Publicat a:Oncotarget
Autors principals: Campa, Victor M., Baltziskueta, Eder, Bengoa-Vergniory, Nora, Gorroño-Etxebarria, Irantzu, Wesołowski, Radosław, Waxman, Jonathan, Kypta, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226675/
https://ncbi.nlm.nih.gov/pubmed/25327559
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