The IGF signalling pathway in Wilms tumours - A report from the ENCCA Renal Tumours Biology-driven drug development workshop

It is hypothesised that Wilms tumour (WT) results from aberrant renal development due to its embryonic morphology, associated undifferentiated precursor lesions (termed nephrogenic rests) and embryonic kidney-like chromatin and gene expression profiles. From the study of overgrowth syndrome-associat...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Maschietto, Mariana, Charlton, Jocelyn, Perotti, Daniela, Radice, Paolo, Geller, James I, Pritchard-Jones, Kathy, Weeks, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226664/
https://ncbi.nlm.nih.gov/pubmed/25478630
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