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Association Studies with Imputed Variants Using Expectation-Maximization Likelihood-Ratio Tests

Genotype imputation has become standard practice in modern genetic studies. As sequencing-based reference panels continue to grow, increasingly more markers are being well or better imputed but at the same time, even more markers with relatively low minor allele frequency are being imputed with low...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Huang, Kuan-Chieh, Sun, Wei, Wu, Ying, Chen, Mengjie, Mohlke, Karen L., Lange, Leslie A., Li, Yun
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226494/
https://ncbi.nlm.nih.gov/pubmed/25383782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110679
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