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Bootstrap Restricted Likelihood Ratio Test for the Detection of Rare Variants
In this paper the detection of rare variants association with continuous phenotypes of interest is investigated via the likelihood-ratio based variance component test under the framework of linear mixed models. The hypothesis testing is challenging and nonstandard, since under the null the variance...
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| 發表在: | Curr Genomics |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Bentham Science Publishers
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460223/ https://ncbi.nlm.nih.gov/pubmed/26069459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1389202916666150304234203 |
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