Altered Peptide Ligands Revisited: Vaccine Design through Chemically Modified HLA-A2–Restricted T Cell Epitopes

Virus or tumor Ag–derived peptides that are displayed by MHC class I molecules are attractive starting points for vaccine development because they induce strong protective and therapeutic cytotoxic T cell responses. In thus study, we show that the MHC binding and consequent T cell reactivity against...

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書目詳細資料
發表在:J Immunol
Main Authors: Hoppes, Rieuwert, Oostvogels, Rimke, Luimstra, Jolien J., Wals, Kim, Toebes, Mireille, Bies, Laura, Ekkebus, Reggy, Rijal, Pramila, Celie, Patrick H. N., Huang, Julie H., Emmelot, Maarten E., Spaapen, Robbert M., Lokhorst, Henk, Schumacher, Ton N. M., Mutis, Tuna, Rodenko, Boris, Ovaa, Huib
格式: Artigo
語言:Inglês
出版: AAI 2014
主題:
Antigen Recognition and Responses
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226423/
https://ncbi.nlm.nih.gov/pubmed/25311806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400800
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