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Withaferin A Inhibits STAT3 and Induces Tumor Cell Death in Neuroblastoma and Multiple Myeloma

Signal transducer and activator of transcription 3 (STAT3) is an oncogenic transcription factor that has been implicated in many human cancers and has emerged as an ideal target for cancer therapy. Withaferin A (WFA) is a natural product with promising antiproliferative properties through its associ...

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Pubblicato in:Biochem Insights
Autori principali: Yco, Lisette P, Mocz, Gabor, Opoku-Ansah, John, Bachmann, André S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Libertas Academica 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226392/
https://ncbi.nlm.nih.gov/pubmed/25452693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BCI.S18863
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