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Gigaseal Mechanics: Creep of the Gigaseal under the Action of Pressure, Adhesion, and Voltage

[Image: see text] Patch clamping depends on a tight seal between the cell membrane and the glass of the pipet. Why does the seal have such high electric resistance? Why does the patch adhere so strongly to the glass? Even under the action of strong hydrostatic, adhesion, and electrical forces, it cr...

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Pubblicato in:J Phys Chem B
Autori principali: Slavchov, Radomir I., Nomura, Takeshi, Martinac, Boris, Sokabe, Masahiro, Sachs, Frederick
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226309/
https://ncbi.nlm.nih.gov/pubmed/25295693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp506965v
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