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Improving Physical Properties via C–H Oxidation: Chemical and Enzymatic Approaches
Physicochemical properties constitute a key factor for the success of a drug candidate. Whereas many strategies to improve the physicochemical properties of small heterocycle-type leads exist, complex hydrocarbon skeletons are more challenging to derivatize due to the absence of functional groups. A...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4226272/ https://ncbi.nlm.nih.gov/pubmed/25244630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201407016 |
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