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Efficient BST2 antagonism by Vpu is critical for early HIV-1 dissemination in humanized mice
BACKGROUND: Vpu is a multifunctional accessory protein that enhances the release of HIV-1 by counteracting the entrapment of nascent virions on infected cell surface mediated by BST2/Tetherin. Vpu-mediated BST2 antagonism involves physical association with BST2 and subsequent mislocalization of the...
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| Publicado no: | Retrovirology |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4226203/ https://ncbi.nlm.nih.gov/pubmed/24195843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-128 |
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