The Effect of Inhaled IFN-β on Worsening of Asthma Symptoms Caused by Viral Infections. A Randomized Trial

Rationale: Ex vivo, bronchial epithelial cells from people with asthma are more susceptible to rhinovirus infection caused by deficient induction of the antiviral protein, IFN-β. Exogenous IFN-β restores antiviral activity. Objectives: To compare the efficacy and safety of inhaled IFN-β with placebo...

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Détails bibliographiques
Publié dans:Am J Respir Crit Care Med
Auteurs principaux: Djukanović, Ratko, Harrison, Tim, Johnston, Sebastian L., Gabbay, Flic, Wark, Peter, Thomson, Neil C., Niven, Robert, Singh, Dave, Reddel, Helen K., Davies, Donna E., Marsden, Richard, Boxall, Christine, Dudley, Sarah, Plagnol, Vincent, Holgate, Stephen T., Monk, Phillip
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2014
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226052/
https://ncbi.nlm.nih.gov/pubmed/24937476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201312-2235OC
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