The Effect of Inhaled IFN-β on Worsening of Asthma Symptoms Caused by Viral Infections. A Randomized Trial

Rationale: Ex vivo, bronchial epithelial cells from people with asthma are more susceptible to rhinovirus infection caused by deficient induction of the antiviral protein, IFN-β. Exogenous IFN-β restores antiviral activity. Objectives: To compare the efficacy and safety of inhaled IFN-β with placebo...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Djukanović, Ratko, Harrison, Tim, Johnston, Sebastian L., Gabbay, Flic, Wark, Peter, Thomson, Neil C., Niven, Robert, Singh, Dave, Reddel, Helen K., Davies, Donna E., Marsden, Richard, Boxall, Christine, Dudley, Sarah, Plagnol, Vincent, Holgate, Stephen T., Monk, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226052/
https://ncbi.nlm.nih.gov/pubmed/24937476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201312-2235OC
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