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Dysregulation of Claudin-5 in HIV-induced Interstitial Pneumonitis and Lung Vascular Injury. Protective Role of Peroxisome Proliferator–activated Receptor-γ

Rationale: HIV-1–induced interstitial pneumonitis (IP) is a serious complication of HIV-1 infection, characterized by inflammation and cellular infiltration in lungs, often leading to respiratory failure and death. The barrier function of the pulmonary endothelium is caused in part by tight junction...

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Bibliografske podrobnosti
izdano v:Am J Respir Crit Care Med
Main Authors: Li, Hong, Singh, Sangya, Potula, Raghava, Persidsky, Yuri, Kanmogne, Georgette D.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226025/
https://ncbi.nlm.nih.gov/pubmed/22345580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201106-1151OC
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