Activation of Peroxisome Proliferator-Activated Receptor gamma (PPARγ)() suppresses Rho GTPases in human brain microvascular endothelial cells and inhibits adhesion and transendothelial migration of HIV-1 infected monocytes()

Under inflammatory conditions (including HIV-1 encephalitis and multiple sclerosis), activated brain endothelium enhances the adhesion and transmigration of monocytes across the blood-brain barrier (BBB). Synthetic ligands that activate the peroxisome proliferator-activated receptors (PPARs) have an...

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Auteurs principaux: Ramirez, Servio H., Heilman, David, Morsey, Brenda, Potula, Raghava, Haorah, James, Persidsky, Yuri
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384722/
https://ncbi.nlm.nih.gov/pubmed/18209083
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