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Thermodynamic Analysis of Mutant lac Repressors

The lactose (lac) repressor is an allosteric protein that can respond to environmental changes. Mutations introduced into the DNA binding domain and the effector binding pocket affect the repressor’s ability to respond to its environment. We have demonstrated how the observed phenotype is a conseque...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Daber, Robert, Sochor, Matthew A., Lewis, Mitchell
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225698/
https://ncbi.nlm.nih.gov/pubmed/21459098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.03.057
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