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Thermodynamic Analysis of Mutant lac Repressors

The lactose (lac) repressor is an allosteric protein that can respond to environmental changes. Mutations introduced into the DNA binding domain and the effector binding pocket affect the repressor’s ability to respond to its environment. We have demonstrated how the observed phenotype is a conseque...

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Publicat a:J Mol Biol
Autors principals: Daber, Robert, Sochor, Matthew A., Lewis, Mitchell
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225698/
https://ncbi.nlm.nih.gov/pubmed/21459098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.03.057
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