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What lessons can be learned from the GIST paradigm that can be applied to other kinase-driven cancers
Gastrointestinal stromal tumor (GIST) is the most common sarcoma of the intestinal tract, known to be notoriously refractory to conventional chemotherapy or radiation. It is an ideal solid tumor model to apply our understanding from aberrant signal transduction to drug development, since nearly all...
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| Publicado no: | J Pathol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4225081/ https://ncbi.nlm.nih.gov/pubmed/21125679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2798 |
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