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What lessons can be learned from the GIST paradigm that can be applied to other kinase-driven cancers
Gastrointestinal stromal tumor (GIST) is the most common sarcoma of the intestinal tract, known to be notoriously refractory to conventional chemotherapy or radiation. It is an ideal solid tumor model to apply our understanding from aberrant signal transduction to drug development, since nearly all...
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| 出版年: | J Pathol |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4225081/ https://ncbi.nlm.nih.gov/pubmed/21125679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2798 |
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