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What lessons can be learned from the GIST paradigm that can be applied to other kinase-driven cancers

Gastrointestinal stromal tumor (GIST) is the most common sarcoma of the intestinal tract, known to be notoriously refractory to conventional chemotherapy or radiation. It is an ideal solid tumor model to apply our understanding from aberrant signal transduction to drug development, since nearly all...

詳細記述

保存先:
書誌詳細
出版年:J Pathol
第一著者: Antonescu, Cristina
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225081/
https://ncbi.nlm.nih.gov/pubmed/21125679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2798
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