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Cerebrospinal-fluid exposure of efavirenz and its major metabolites when dosed at 400 and 600 mg once daily; a randomized controlled trial
INTRODUCTION: The optimal penetration of antiretroviral agents into central nervous system (CNS) may be a balance between providing adequate drug exposure to inhibit HIV-replication whilst avoiding concentrations associated with toxicities. METHODS: Cerebrospinal-fluid (CSF) exposure of efavirenz an...
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| Publicado no: | J Int AIDS Soc |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International AIDS Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4224808/ https://ncbi.nlm.nih.gov/pubmed/25394049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7448/IAS.17.4.19541 |
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