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SR-A and SREC-I binding peptides increase HDAd-mediated liver transduction
Helper-dependent adenoviral (HDAd) vectors can mediate long-term, high-level transgene expression from transduced hepatocytes without inducing chronic toxicity. However, vector therapeutic index is narrow because of a toxic acute response with potentially lethal consequences elicited by high vector...
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| 發表在: | Gene Ther |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4224584/ https://ncbi.nlm.nih.gov/pubmed/25119377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2014.71 |
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