SR-A and SREC-I Are Kupffer and Endothelial Cell Receptors for Helper-dependent Adenoviral Vectors

Helper-dependent adenoviral (HDAd) vectors can mediate long-term, high-level transgene expression from transduced hepatocytes with no chronic toxicity. However, a toxic acute response with potentially lethal consequences has hindered their clinical applications. Liver sinusoidal endothelial cells (L...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Piccolo, Pasquale, Vetrini, Francesco, Mithbaokar, Pratibha, Grove, Nathan C, Bertin, Terry, Palmer, Donna, Ng, Philip, Brunetti-Pierri, Nicola
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2013
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616528/
https://ncbi.nlm.nih.gov/pubmed/23358188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.287
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg