Intrathecal Injection of Helper-Dependent Adenoviral Vectors Results in Long-Term Transgene Expression in Neuroependymal Cells and Neurons

Helper-dependent adenoviral (HDAd) vectors are devoid of all viral genes and result in long-term transgene expression in the absence of chronic toxicity. Because of their ability to infect post-mitotic cells, including cells of the central nervous system, HDAd vectors are particularly attractive for...

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Bibliographic Details
Main Authors: Dindot, Scott, Piccolo, Pasquale, Grove, Nathan, Palmer, Donna, Brunetti-Pierri, Nicola
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2011
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155126/
https://ncbi.nlm.nih.gov/pubmed/21175294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.147
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