Shear stress-induced NO production is dependent on ATP autocrine signaling and capacitative calcium entry

Flow-induced production of nitric oxide (NO) by endothelial cells plays a fundamental role in vascular homeostasis. However, the mechanisms by which shear stress activates NO production remain unclear due in part to limitations in measuring NO, especially under flow conditions. Shear stress elicits...

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Udgivet i:Cell Mol Bioeng
Main Authors: Andrews, Allison M., Jaron, Dov, Buerk, Donald G., Barbee, Kenneth A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224574/
https://ncbi.nlm.nih.gov/pubmed/25386222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-014-0351-x
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