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Reconciling the regulatory role of Munc18 proteins in SNARE-complex assembly

Membrane fusion is essential for human health, playing a vital role in processes as diverse as neurotransmission and blood glucose control. Two protein families are key: (1) the Sec1p/Munc18 (SM) and (2) the soluble N-ethylmaleimide-sensitive attachment protein receptor (SNARE) proteins. Whilst the...

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Bibliographische Detailangaben
Veröffentlicht in:IUCrJ
Hauptverfasser: Rehman, Asma, Archbold, Julia K., Hu, Shu-Hong, Norwood, Suzanne J., Collins, Brett M., Martin, Jennifer L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224468/
https://ncbi.nlm.nih.gov/pubmed/25485130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252514020727
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